By Akigrel - 24.03.2020
Paragon hf sec
PARAGON-HF trial presented in a Hot Line Session today at ESC Congress together with WCC. 01 Sep Topic(s). Heart Failure. Paris, France – 1. Patients with heart failure and preserved ejection nal the results of a landmark trial, PARAGON-HF primary end point, we learn more from the sec-.
Secondary outcomes: NYHA class improvement: Symptom improvement was less in women than men.
Association of sacubitril-valsartan initiation from HF hospitalization and benefit: Sacubitril-valsartan vs. There was less decline in renal function among the sacubitril-valsartan group.
There was possible benefit for sacubitril-valsartan among those with EF in the lower range of eligibility.
One-half of enrolled subjects were women and paragon hf sec appeared to be treatment interaction according to sex.
paragon hf sec NT-proBNP did not identify patients with greater benefit from sacubitril-valsartan. Sacubitril-valsartan was associated with a paragon hf sec of the primary outcome in women, but not in men.
However, women derived less symptom improvement from study medication.
There was possible enhanced benefit when sacubitril-valsartan was initiated in close proximity to the paragon hf sec hospitalization event; however, this finding deserves prospective validation.
HFpEF patients were characterized by a high prevalence of left atrial enlargement, diastolic dysfunction, and pulmonary hypertension. Presented by Dr. J Am Coll Cardiol ; A Call for Deep Paragon hf sec.
Circulation ;Nov [Epub ahead of print]. John J. Paragon hf sec Engl J Med ; Share via:.
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